This iconic New York landmark epitomizes the city's fashion and glamour, from the opulent gold and marble lobby to the specialty themed suites inspired by Dior (above), Tiffany & Co., and Bentley. The amenities at the St. Regis are also first-rate—guests can make use of the Bentley House Car and enjoy attentive hospitality from the hotel's hallmark Butler Service.

Consider this a little oasis of British charm in the middle of urban Manhattan. The Crosby Street Hotel, a charming spot tucked away on a quiet cobblestone street in the heart of SoHo, features eclectic, vintage-inspired decor in its light-filled rooms and bathrooms stocked with products from London-based perfumer Miller Harris. Every day, guests can enjoy a traditional English tea served in The Crosby Bar.

A hip hotel in the trendy Meatpacking District, The Gansevoort is a hotspot at all hours of the day. Hit the rooftop pool to cool off from the city's summer heat and day-drink. Then, come evening, soak up the illuminated city vistas from the terrace or head into one of the hotel's multiple nightlife destinations.

Like a real-life Pinterest board, the High Line Hotel oozes eclectic vintage charm. Furniture is one-of-a-kind and locally sourced to evoke that homey, lived-in feel. Rooms feature large, oversized windows with excellent views of the High Line. Guests can grab a cup of coffee at the downstairs bar before heading out into Chelsea, and upon return, enjoy a glass of wine in the idyllic, Parisian-inspired garden.

Part-owned by Robert de Niro, the Greenwich Hotel maintains an unassuming, quiet comfort. Wood-beamed ceilings and exposed brick are matched in their rustic sensibility by the tufted leather seating and fireplace, while a Japanese influence is evident in the folding room dividers, shoji-style panels, and the serene courtyard garden. The pièce de résistance, however, is the underground pool and Shibui Spa, which sits beneath a 250-year-old bamboo and reclaimed wood roof.

On par in luxury and class with the nearby Four Seasons and Ritz-Carlton hotels, Mandarin Oriental is a sleek, modern counterpoint to its storied neighbors. Perched high above Columbus Circle, the hotel boasts incredible bird's-eye views of Central Park from its spectacular, Asian-inspired rooms. Plus, the world-class Spa at Mandarin Oriental is one of the best in the city.

The spot where many a celebrity gets ready before the Met Gala each year, The Mark is flawlessly elegant in its Jacques Grange-designed interiors and Upper East Side luxury. Grab one of the hotel's custom bikes or hop in a black-and-white striped pedicab to hit up the nearby 5th Avenue boutiques—though you don't have to leave the hotel for the finest in high-end shopping, pampering and dining. The Mark offers room service prepared by renowned chef Jean-Georges Vongerichten, sweet treats by Ladurée, a Frédéric Fekkai salon, and 24/7 access to Bergdorf Goodman for it's penthouse guests.

Elegant and upscale, with a decidedly European feel, the NoMad Hotel is where anyone who wishes she were French should stay. The hotel is housed in a turn-of-the-century Beaux Arts building with interiors by French designer Jacques Garcia, who drew inspiration from his own childhood apartment in Paris. The rooms are cozy, but elegantly appointed, featuring large beds with studded leather headboards, velvet tapestries, antique Heriz rugs, and free-standing clawfoot bathtubs. C'est très chic.

The Bowery is one of those of-the-moment but understated spots that draws in the chicest of fashion insider and celebrity crowds. The decor is rustic and inviting in the lobby, and luxe yet airy in the guest rooms with factory-style floor-to-ceiling windows letting in the perfect light for a envy-inducing Instagram shot.